One Stop GATE Forum: GATE Life Sciences Sample Papers

Message


   Sample 
                                      Papers
                                  
                                   
                                     
                                  
                                   
                                     Q.1 
                                      In corn there are 10 chromosomes per set 
                                      and the species is diploid. A karyotype 
                                      was performed from the endosperm cells grown 
                                      in tissue culture in a medium containing 
                                      colchicine. What is the total number of 
                                      chromosomes in an endosperm cell after the 
                                      first round of cell divisions? 
                                      
                                         
                                          (a) 5
                                        
                                         
                                          (b) 14
                                        
                                         
                                          (c) 15
                                        
                                         
                                          (d) 30
                                        
                                      
                                  
                                   
                                    Q.2 
                                      Three of the four eukaryotic rRNAs are synthesized 
                                      from a single transcription unit consisting 
                                      of the rDNA. Which one of the following 
                                      does NOT belong to this group?
 
                                         
                                          (a) 5.8S
                                        
                                         
                                          (b) 5S
                                        
                                         
                                          (c) 18S
                                        
                                         
                                          (d) 28S
                                        
                                      
                                  
                                   
                                    Q.3 
                                      When ß-[³² P]-ATP is incubated 
                                      in an eukaryotic cell extract that is capable 
                                      of transcription and RNA processing where 
                                      does the label appear in the m-RNA?
 
                                      
                                         
                                          (a) Every phosphate 
                                            group of the m RNA is labelled
                                        
                                         
                                          (b) Only the 5-end of 
                                            the m RNA is labelled provided the 
                                            first base is A
                                        
                                         
                                          (c) Only the 3-end of 
                                            the m-RNA is labelled provided the 
                                            last base is A
                                        
                                         
                                          (d) The label does not 
                                            appear at all in m-RNA
                                        
                                      
                                  
                                   
                                    Q.4 
                                      Which particle converts 
                                      cholesterol to cholesterol esters? 
 
                                      
                                         
                                          (a) LDL
                                        
                                         
                                          (b) Chylomicrons
                                        
                                         
                                          (c) VLDL
                                        
                                         
                                          (d) HDL
                                        
                                      
                                  
                                   
                                    Q.5 
                                      A patient presents with 
                                      lethargy and a 10-fold increase in plasma 
                                      ammonia and glutamine levels due to a defect 
                                      in the urea cycle. The build-up of what 
                                      other metabolite in the plasma is consistent 
                                      with a defect in ornithine transcarbamoylase 
                                      and not carbamoyl phosphate synthetase I? 
                                      
                                         
                                          (a) Urea
                                        
                                         
                                          (b) Arginine
                                        
                                         
                                          (c) Ornithine
                                        
                                         
                                          (d) Citrulline
                                        
                                      
                                  
                                   
                                    Q.6 
                                      Tay-Sachs Disease, characterized 
                                      by intralysosomal accumulation of the GM2 
                                      ganglioside, results from a deficiency in 
                                      
                                         
                                          (a) Sphingomyelinase. 
                                        
                                         
                                          (b) Galactocerebrosidase. 
                                        
                                         
                                          (c) Glucocerebrosidase. 
                                        
                                         
                                          (d) Hexosaminidase A. 
                                        
                                      
                                  
                                   
                                    Q.7 
                                      Which of the following assays is currently 
                                      being used for the detection of Helicobacter 
                                      pylori? 
                                      
                                         
                                          (a) Agglutination
                                        
                                         
                                          (b) Complement fixation
                                        
                                         
                                          (c) Enzyme-linked immunosorbent 
                                            assay
                                        
                                         
                                          (d) Immunodiffusion
                                        
                                      
                                  
                                   
                                    Q.8 
                                      An individual was found to be heterolo-gous 
                                      for IgG₁ allotypes 3 and 12. 
                                      The different possible IgG₁ antibodies 
                                      produced by this individual will never have 
                                      
                                         
                                          (a) Two H chains of allotype 12
                                        
                                         
                                          (b) Two L chains of either Κ 
                                            or Λ
                                        
                                         
                                          (c) Two H chains of allotype 3
                                        
                                         
                                          (d) Two H chains, one of allotype 
                                            3 and one of allotype 12
                                        
                                      
                                  
                                   
                                    Q.9 
                                      The resting membrane potential
 
                                      
                                         
                                          (a) Occurs only in nerve and muscle 
                                            cells
                                        
                                         
                                          (b) Is the same in all cells.
                                        
                                         
                                          (c) Is oriented so that the cell's 
                                            interior is positive with respect 
                                            to the extracellular fluid.
                                        
                                         
                                          (d) Requires the separation of most 
                                            of the cell's charged particles.
                                        
                                      
                                  
                                   
                                    Q.10 
                                      Which of the following is 
                                      NOT part of Koch's postulates? 
                                      
                                         
                                          (a) The microorganism is never found 
                                            in healthy animals.
                                        
                                         
                                          (b) The microorganisms is always 
                                            found in diseased animals.
                                        
                                         
                                          (c) The microorganism must cause 
                                            disease in healthy animals.
                                        
                                         
                                          (d) The microorganism must secrete 
                                            a toxin in culture.


One Stop GATE Forum : GATE AT A GLANCE : Test Series